Library

3,3-Diethyl-2-pyrrolidinone

Share on Facebook Share on Twitter Email
Wikipedia on Answers.com:

3,3-Diethyl-2-pyrrolidinone

Top
Home > Library > Miscellaneous > Wikipedia
3,3-Diethyl-2-pyrrolidinone
Systematic (IUPAC) name
3,3-diethyl-2-pyrrolidinone
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 175698-05-2
ATC code None
PubChem CID 9793807
ChemSpider 7969574 YesY
ChEMBL CHEMBL293075 YesY
Chemical data
Formula C8H15NO 
Mol. mass 141.210 g/mol
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

3,3-Diethyl-2-pyrrolidinone (DEABL) is an anticonvulsant drug most closely related to pyrithyldione and gabapentin.[1] It was found to extend lifespan in nematode worms.[2]

References

  1. ^ Hill, MW; Reddy, PA; Covey, DF; Rothman, SM (1998). "Contribution of subsaturating GABA concentrations to IPSCs in cultured hippocampal neurons". Journal of Neuroscience 18 (14): 5103–11. PMID 9651194. 
  2. ^ Evason, K; Huang, C; Yamben, I; Covey, DF; Kornfeld, K (2005). "Anticonvulsant medications extend worm life-span". Science 307 (5707): 258–62. doi:10.1126/science.1105299. PMID 15653505. 
v · d · eAnticonvulsants (N03)
GABAA receptor agonist
Other GABA agents
Carbonic anhydrase inhibitor
Channel blockers
Primarily sodium
Primarily calcium
Unknown/ungrouped
Channel openers
Indirect GABA agents
Unknown/multiple/
unsorted
#WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III
v · d · eGABAergics
Receptor
ligands

Agonists: Main site: Bamaluzole • Gaboxadol • Ibotenic acid • Isoguvacine • Isonipecotic acid • Muscimol (Amanita Muscaria) • Progabide • SL 75102 • Thiomuscimol • Tolgabide; Positive allosteric modulators: Barbiturates • Benzodiazepines • Carbamates • Chlormezanone • Clomethiazole • Ethanol (Alcohol) • Etomidate • Kavalactones (Kava) • Loreclezole • Metomidate • Neuroactive steroids • Nonbenzodiazepines (β-Carbolines, Cyclopyrrolones, Imidazopyridines, Pyrazolopyrimidines, etc.) • Phenols • Piperidinediones • Propanidid • Pyrazolopyridines • Quinazolinones • ROD-188 • Skullcap • Stiripentol • Valerenic acid (Valerian)
* See Template:GABAAergics for a full list of GABAA positive allosteric modulators.

Antagonists: Main site: Bicuculline • Gabazine • Pitrazepin; Negative allosteric modulators: α5IA • Bilobalide • Cicutoxin • Cyclothiazide • DMCM • Flumazenil • Flurothyl • Furosemide • L-655,708 • Oenanthotoxin • Penicillin • Pentylenetetrazol • Picrotoxin • PWZ-029 • Ro15-4513 • Sarmazenil • Suritozole • Thujone (Absinthe) • Thiocolchicoside • ZK-93426
Agonists: Main site: 1,4-Butanediol • Baclofen • GBL • GHB • GHV • GVL • Lesogaberan • Phenibut • Progabide • SKF-97,541 • Tolgabide; Positive allosteric modulators: BHF-177 • BHFF • BSPP • CGP-7930 • GS-39783
Antagonists: Main site: CGP-35348 • Phaclofen • Saclofen • SCH-50911
Agonists: Main site: CACA • CAMP • GABOB • N(4)-chloroacetylcytosine arabinoside • Progabide • Tolgabide
Antagonists: Main site: Bilobalide • TPMPA
Reuptake
inhibitors
GAT inhibitors
CI-966 • Deramciclane • EF-1502 • Gabaculine • Guvacine • Nipecotic acid • NNC 05-2090 • SKF-89976A • SNAP-5114 • Tiagabine
Enzyme
inhibitors
GAD inhibitors
GABA-T inhibitors
3-Hydrazinopropionic acid • Aminooxyacetic acid • Gabaculine • Isoniazid • Phenelzine • Phenylethylidenehydrazine • Sodium valproate • Valnoctamide • Valproate pivoxil • Valproate semisodium (Divalproex sodium) • Valproic acid • Valpromide • Vigabatrin
Others
Others


Stub icon This anticonvulsant-related article is a stub. You can help Wikipedia by expanding it.

This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)

Post a question - any question - to the WikiAnswers community:

Copyrights:

Cite
Wikipedia on Answers.com This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article 3,3-Diethyl-2-pyrrolidinone. Read more

Featured guides

» More