3,4-Dihydroxymandelic acid

3,4-Dihydroxymandelic acid
IUPAC name 2-(3,4-dihydroxyphenyl)-2-hydroxyacetic acid
Identifiers
CAS number	775-01-9
PubChem	85782
ChemSpider	77371 Y
KEGG	C05580 Y
MeSH	3,4-dihydroxymandelic+acid
ChEBI	CHEBI:27637 Y
Jmol-3D images	Image 1
SMILES O=C(O)C(O)c1cc(O)c(O)cc1
InChI InChI=1S/C8H8O5/c9-5-2-1-4(3-6(5)10)7(11)8(12)13/h1-3,7,9-11H,(H,12,13) Y Key: RGHMISIYKIHAJW-UHFFFAOYSA-N Y InChI=1/C8H8O5/c9-5-2-1-4(3-6(5)10)7(11)8(12)13/h1-3,7,9-11H,(H,12,13) Key: RGHMISIYKIHAJW-UHFFFAOYAB
Properties
Molecular formula	C8H8O5
Molar mass	184.14612
Y acid (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

3,4-Dihydroxymandelic acid (DHMA, DOMA) is a metabolite of norepinephrine.^[1]

Norepinephrine degradation. 3,4-Dihydroxymandelic acid is shown at right. Enzymes are shown in boxes. ^[2]

References

1. ^ Ley JP, Engelhart K, Bernhardt J, Bertram HJ (October 2002). "3,4-Dihydroxymandelic acid, a noradrenalin metabolite with powerful antioxidative potential". J. Agric. Food Chem. 50 (21): 5897–902. doi:10.1021/jf025667e. PMID 12358456. 
2. ^ Figure 11-4 in: Rod Flower; Humphrey P. Rang; Maureen M. Dale; Ritter, James M. (2007). Rang & Dale's pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-06911-5. 

v · d · eNeurotransmitter metabolic intermediates catecholamines Anabolism (tyrosine→epinephrine) Tyrosine → Levodopa → Dopamine → Norepinephrine → Epinephrine Catabolism/ metabolites dopamine: DOPAL · DOPAC · MOPET · Hydroxytyrosol · 3-Methoxytyramine · Homovanillic acid norepinephrine: 3,4-Dihydroxymandelic acid · Normetanephrine · Vanillylmandelic acid · 3-Methoxy-4-hydroxyphenylglycol · Dihydroxyphenylethylene glycol epinephrine: Metanephrine tryptophan→serotonin anabolism: 5-Hydroxytryptophan catabolism: 5-Hydroxyindoleacetic acid serotonin→melatonin Normelatonin M: MET mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)

This article about an aromatic compound is a stub. You can help Wikipedia by expanding it.v · d · e

This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)