6-APB

6-APB

Systematic (IUPAC) name
6-(2-aminopropyl)benzofuran
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	286834-85-3 N 286834-84-2 (hydrochloride)
ATC code	None
PubChem	CID 9794343
ChemSpider	7970110 Y
Chemical data
Formula	C11H13NO
Mol. mass	175.23 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C11H13NO/c1-8(12)6-9-2-3-10-4-5-13-11(10)7-9/h2-5,7-8H,6,12H2,1H3 Y Key:FQDAMYLMQQKPRX-UHFFFAOYSA-N Y
N (what is this?)  (verify)

6-(2-aminopropyl)benzofuran or 1-benzofuran-6-ylpropan-2-amine (6-APB or Benzo Fury) is thought to be a stimulant and entactogen drug although to date, no authoritative source can say even whether or not it is psychoactive. It was first identified being sold as a designer drug in 2012.^[1] Chemically, it is of the phenethylamine and substituted amphetamine classes. It is similar to MDA in that the 3,4-methylenedioxyphenyl ring system has been replaced with a benzofuran ring. 6-APB is also the unsaturated benzofuran derivative of 6-APDB. There is currently no toxicology data available.

Pharmacology

6-APB has not been properly assessed in terms of pharmacological action, but based on its chemical similarity to other amphetamines and methylenedioxy compounds, it likely acts as a releasing agent and reuptake inhibitor of serotonin, norepinephrine, and dopamine.^{[citation needed]} Though its effects on monoamine release have not been validated, 6-APB has been claimed to act as an agonist of the 5-HT_2C receptor.^[2] It may also act as an agonist of the 5-HT_2A and 5-HT_2B receptors, the former likely explaining its reputed psychedelic effects.

Law

6-APB is not listed under the Opium Law or the Medicine Act in the Netherlands, and thus currently legal.

6-APB is unscheduled in the United States. However, this chemical may be covered under the Federal Analogue Act in the United States.

Certain countries contain a "substantially similar" catch-all clause in their drug law, such as New Zealand and Australia. This includes 6-APB as it is in some respects similar in chemical structure to the class A drug MDA^{[citation needed]}, meaning 6-APB may be viewed as a controlled substance analogue in these jurisdictions.^[3]

6-APB is unscheduled under the Controlled Drugs and Substances Act (CDSA) in Canada, although there is a Schedule III amphetamine analogue clause. Due to 6-APB's structure, it may be considered an analogue of MDA, but these types of offenses are rarely prosecuted.^{[citation needed]} Canada's CDSA defines an analogue as any substance that, in relation to a controlled substance, has a substantially similar chemical structure.

6-APB is currently legal in the UK.

6-APB is currently legal in Germany. If consumption is intended however, the German drug law takes effect automatically, prohibiting production and disposal.^[4]

See also

• 5-APB
• 5-APDB
• 6-APDB
• 5-(2-Aminopropyl)indole
• Ethylenedioxymethamphetamine
• Indanylaminopropane
• Naphthylaminopropane
• Tetralinylaminopropane

References

[Synthesis:http://www.xfactorchemicals.com/images/synthesis/6-apb-benzo-fury-synthesis-.html]