6-Methyl-MDA

6-Methyl-MDA

Systematic (IUPAC) name
1-(6-methyl-1,3-benzodioxol-5-yl)propan-2-amine
Clinical data
Pregnancy cat.	?
Legal status	Uncontrolled (but may be covered under the Federal Analogue Act in the United States and under similar bills in other countries)
Routes	Oral
Identifiers
ATC code	None
PubChem	CID 10511982
ChemSpider	8687383 Y
ChEMBL	CHEMBL6376 Y
Chemical data
Formula	C11NO2
Mol. mass	193.24 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C11H15NO2/c1-7-3-10-11(14-6-13-10)5-9(7)4-8(2)12/h3,5,8H,4,6,12H2,1-2H3 Y Key:HCFHWXDIZOAUTQ-UHFFFAOYSA-N Y
Y (what is this?)  (verify)

6-Methyl-3,4-methylenedioxyamphetamine (6-Methyl-MDA) is an entactogen and psychedelic drug of the amphetamine class.^[1] It was first synthesized in the late 1990s by a team including David E. Nichols at Purdue University while investigating derivatives of MDA and MDMA.^[1]

6-Methyl-MDA has IC₅₀ values of 783nM, 28,300nM, and 4,602nM for inhibiting the reuptake of serotonin, dopamine, and norepinephrine in rat synaptosomes.^[1] In animal studies it substitutes for MBDB, MMAI, LSD, and DOI, though not amphetamine, but only partially and at high doses.^[1] Thus, while several-fold less potent than its analogues 2-methyl-MDA and 5-methyl-MDA, and approximately half as potent as MDA, 6-methyl-MDA is still significantly active,^[1] and appropriate doses may be similar to or somewhat higher than those of MDMA.^{[citation needed]}

See also

• 2-Methyl-MDA
• 5-Methyl-MDA
• MMDA-2
• MADAM-6

References