6-phosphofructokinase 1

An enzyme of the glycolytic (Embden–Meyerhof) pathway that catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate using ATP as the source of the phosphate. Allosteric enzyme regulating glycolysis.

• p. deficiency — inherited disorder of glucose metabolism in English springer spaniel dogs. Affected dogs develop a chronic hemolytic anemia. Called also Type 7 glycogen storage disease.