PTH stands for parathyroid hormone. It is a protein hormone released by the parathyroid gland. PTH is the most important regulator of the body's calcium and phosphorus levels.
Release of PTH is controlled by the level of calcium in the blood. Low blood calcium levels cause increased PTH to be released, while high blood calcium levels inhibit PTH release.
A laboratory test can be done to measure the amount of PTH in your blood.
Alternative NamesParathormone; Parathormone (PTH) intact molecule; Parathyroid hormone
How the test is performedBlood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.
Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm.
Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.
In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.
How to prepare for the testYou should not eat or drink anything except water for 10 to 12 hours before the test.
How the test will feelWhen the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.
Why the test is performedYour doctor may order this test if you have abnormal calcium or phosphorus levels and a PTH abnormality is suspected.
Normal ValuesNormal values are 10-55 picograms per milliliter (pg/mL). Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
What abnormal results meanGreater-than-normal levels may occur with:
Lower-than-normal levels may occur with:
Other conditions under which the test may be performed:
Wysolmerski JJ, Insogna KL. The parathyroid glands, hypercalcemia, and hypocalcemia. In: Kronenberg HM, Schlomo M, Polansky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. St. Louis, MO: WB Saunders;2008:chap 266.