Acanthosis

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Acanthosis

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Not to be confused with Acantholysis.

Acanthosis is diffuse epidermal hyperplasia.^[1] It implies increased thickness of the Malpighian layer (stratum basale and stratum spinosum).^[2]

References

^ Kumar, Vinay; Fausto, Nelso; Abbas, Abul (2004) Robbins & Cotran Pathologic Basis of Disease (7th ed.). Saunders. Page 1230. ISBN 0-7216-0187-1.
^ "Acanthosis". DermPathTutor. Department of Dermatology, University of Iowa. September 1995. http://www.healthcare.uiowa.edu/dermatology/dpt/Acanthosis.htm. Retrieved 17 May 2012.

Clinical and histological nomenclature for skin lesions

Macroscopic

Primary lesions	flat (Macule, Patch) · elevated (Papule, Nodule, Plaque) · fluid (Vesicle, Bulla, Pustule) · Ulcer · Erosion · Telangiectasia Special initial lesions : Burrow (Tunnel) · Comedone · Scutulum · Target lesion · Herald patch · Wheal

Secondary lesions	Scale · Crust · Lichenification · Excoriation · Induration · Atrophy

Microscopic

keratin: Hyperkeratosis · Parakeratosis · Dyskeratosis

Hypergranulosis · Acanthosis · Papillomatosis · Acantholysis · Spongiosis · Hydropic swelling · Exocytosis · Vacuolization · Erosion · Ulceration · Lentiginous

Cutaneous keratosis, ulcer, atrophy, and necrobiosis (L82–L94, 700–701.5)

Epidermal thickening

keratoderma: Keratoderma climactericum • Paraneoplastic keratoderma (Acrokeratosis paraneoplastica of Bazex ) • Aquagenic keratoderma · Drug-induced keratoderma · Paraneoplastic keratoderma • psoriasis (Keratoderma blennorrhagica)

keratosis: Seborrheic keratosis (Clonal seborrheic keratosis · Common seborrheic keratosis · Irritated seborrheic keratosis · Seborrheic keratosis with squamous atypia · Reticulated seborrheic keratosis · Dermatosis papulosa nigra) • Keratosis punctata of the palmar creases

other hyperkeratosis: Acanthosis nigricans (Confluent and reticulated papillomatosis) · Callus • Ichthyosis acquisita · Arsenical keratosis · Chronic scar keratosis · Hyperkeratosis lenticularis perstans · Hydrocarbon keratosis · Hyperkeratosis of the nipple and areola · Inverted follicular keratosis · Lichenoid keratosis · Multiple minute digitate hyperkeratosis · PUVA keratosis · Reactional keratosis · Stucco keratosis · Thermal keratosis · Viral keratosis · Warty dyskeratoma · Waxy keratosis of childhood

other hypertrophy: Keloid · Hypertrophic scar • Cutis verticis gyrata ·

Necrobiosis/granuloma

Necrobiotic/palisading	Granuloma annulare (Perforating, Generalized, Subcutaneous, Granuloma annulare in HIV disease, Localized granuloma annulare, Patch-type granuloma annulare) · Necrobiosis lipoidica · Annular elastolytic giant cell granuloma · Granuloma multiforme · Necrobiotic xanthogranuloma · Palisaded neutrophilic and granulomatous dermatitis · Rheumatoid nodulosis · Interstitial granulomatous dermatitis/Interstitial granulomatous drug reaction

Foreign body granuloma	Beryllium granuloma • Mercury granuloma • Silica granuloma • Silicone granuloma • Zirconium granuloma • Soot tattoo • Tattoo • Carbon stain

Other/ungrouped	eosinophilic dermatosis (Granuloma faciale)

Dermis/
localized CTD

Cutaneous lupus erythematosus	chronic: Discoid · Panniculitis subacute: Neonatal ungrouped: Chilblain · Lupus erythematosus–lichen planus overlap syndrome · Tumid · Verrucous · Rowell's syndrome

Scleroderma/ Morphea	Localized scleroderma (Localized morphea, Morphea–lichen sclerosus et atrophicus overlap, Generalized morphea, Atrophoderma of Pasini and Pierini, Pansclerotic morphea, Morphea profunda, Linear scleroderma)

Atrophic/ atrophoderma	Lichen sclerosus · Anetoderma (Schweninger–Buzzi anetoderma, Jadassohn–Pellizzari anetoderma) · Atrophoderma of Pasini and Pierini · Acrodermatitis chronica atrophicans · Semicircular lipoatrophy · Follicular atrophoderma · Linear atrophoderma of Moulin

Perforating	Kyrle disease · Reactive perforating collagenosis · Elastosis perforans serpiginosa · Perforating folliculitis · Acquired perforating dermatosis

Skin ulcer	Pyoderma gangrenosum

Other	Calcinosis cutis · Sclerodactyly · Poikiloderma vasculare atrophicans · Ainhum/Pseudo-ainhum

M: INT, SF, LCT

anat/phys/devp

noco(i/b/d/q/u/r/p/m/k/v/f)/cong/tumr(n/e/d), sysi/epon

proc, drug (D2/3/4/5/8/11)

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