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An accession number in bioinformatics is a unique identifier given to a DNA or protein sequence record to allow for tracking of different versions of that sequence record and the associated sequence over time in a single data repository. Because of its relative stability, accession numbers can be utilized as foreign keys for referring to a sequence object, but not necessarily to a unique sequence. All sequence information repositories implement the concept of "accession number" but might do so with subtle variations.
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Locus Reference Genomic (LRG) records have unique accession numbers starting with LRG_ followed by a number. They are recommended in the Human Genome Variation Society Nomenclature guidelines as stable genomic reference sequences to report sequence variants in LSDBs and the literature.
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