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Brand names: Cold Multi-Symptom Daytime , Comtrex® Cold and Cough Non-Drowsy , Little Colds® Multisymptom, Mapap Multi-Symptom Cold, Theraflu® Severe Cold Daytime, Tylenol® Cold Head Congestion Daytime Non-Drowsy, Tylenol® Cold Multi-Symptom Daytime Non-Drowsy, Tylenol® Infants Cold and Cough

Acetaminophen; Dextromethorphan; Phenylephrine liquicaps

What are Acetaminophen; Dextromethorphan; Phenylephrine liquicaps?

ACETAMINOPHEN, DEXTROMETHORPHAN, AND PHENYLEPHRINE (Vicks DayQuil® LiquiCaps) are used together to decrease symptoms caused by colds or the flu. Acetaminophen helps lower fever, and relieve muscle aches, headache, and sore throat pain. Dextromethorphan helps to stop cough. Phenylephrine helps reduce nasal and sinus congestion.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
• alcohol use
• anemia or blood disease
• asthma, emphysema, bronchitis, or other lung disease
• chronic cough
• diabetes
• difficulty or pain passing urine or other bladder problems
• enlarged prostate
• G6PD deficiency
• glaucoma
• hardening of the arteries
• heart disease including angina, history of heart attack, blockage in heart vessels, enlarged heart, heart failure
• hepatitis
• high blood pressure
• history of stroke, mini-strokes (TIAs), or aneurysm
• infection
• problems with immune system
• irregular heart beat
• kidney disease
• liver disease
• poor circulation (peripheral vascular disease)
• over active thyroid
• an unusual reaction to Acetaminophen, Dextromethorphan, Phenylephrine, Aspirin, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should this medicine be used?

Take this medicine by mouth with plenty of water. Follow the directions on the label. Take it with food or milk if it upsets your stomach. Take your doses at regular intervals. Do not take your medicine more often than directed.

Try to avoid grapefruit juice while using this medicine because this may increase the chance of side effects from dextromethorphan.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you are taking this medicine regularly and miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What drug(s) may interact with Acetaminophen; Dextromethorphan; Phenylephrine?

• atomoxetine
• atropine
• busulfan
• caffeine
• cholestyramine
• cocaine
• delavirdine
• ergot medicines like ergotamine or ergonovine
• exenatide
• furazolidone
• gefitinib
• grapefruit juice
• imatinib
• isoniazid
• linezolid
• mecamylamine
• medicines for chest pain, heart disease, high blood pressure, or heart rhythm problems
• medicine for diabetes
• medicines known as MAO inhibitors, like phenelzine (Nardil®), tranylcypromine (Parnate®), isocarboxazid (Marplan®), and selegiline (Carbex®, Eldepryl®)
• medicines for mental depression, like fluoxetine (Prozac®), sertraline (Zoloft®), and paroxetine (Paxil®)
• medicines for mental problems and psychotic disturbances
• medicines for weight loss
• midodrine
• phenytoin or fosphenytoin
• prilocaine
• procarbazine
• rifabutin
• rifampin
• ritonavir
• ropinirole
• St. John's wort
• sulfinpyrazone
• terbinafine
• theophylline
• thyroid hormones
• valdecoxib
• warfarin
• zidovudine

Because this product can cause drowsiness, other medicines that also cause drowsiness may increase this effect. Some medicines that cause drowsiness are:
• alcohol and alcohol-containing medicines
• barbiturate medicines for inducing sleep or treating seizures (convulsions)
• medicines for anxiety or sleeping problems, such as diazepam or temazepam
• medicines for hay fever and other allergies
• medicines for movement abnormalities as in Parkinson's disease
• muscle relaxers
• prescription pain medicines

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking Acetaminophen; Dextromethorphan; Phenylephrine?

If you have a fever, skin rash, or persistent headache as well as a cough, see your prescriber. Do not treat for fever longer than 3 days, or for congestion, cough, or pain for longer than 7 days without consulting a health care professional. If your sore throat is severe, lasts more than 2 days, or if you also have a fever, headache, rash, nausea, and vomiting, see a health care professional immediately.

You may get drowsy or dizzy, although these side effects are uncommon. Do not do anything that needs mental alertness until you know how this medicine affects you. Alcohol can increase the chance of drowsiness, dizziness, or liver problems while using this medicine.

If this medicine makes it difficult for you to sleep at night; take your last dose at least a few hours before bedtime.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water will help.

If you are going to have surgery, tell your prescriber or health care professional that you are taking this medicine.

What side effects may I notice from receiving Acetaminophen; Dextromethorphan; Phenylephrine?

Side effects that you should report to your prescriber or health care professional as soon as possible:
• agitation, nervousness, excitability, not able to sleep
• bloody stools
• chest pain
• confusion
• difficulty breathing, or wheezing
• difficulty urinating
• headache, especially if severe or gets worse
• high blood pressure
• irregular heart beat
• nausea and vomiting
• skin rash or hives
• slurred speech
• tremors
• unusual bleeding or bruising, pinpoint red spots on the skin
• unusual tiredness or weakness
• yellowing of the skin or eyes

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
• loss of appetite
• stomach ache

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.

Last updated: 5/17/2006 7:40:00 PM

Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.