Acetohydroxamic acid
Saunders Veterinary Dictionary:
Top
acetohydroxamic acid
A hydroxamic acid that specifically inhibits urease; it retards alkalinization of the urine caused by urease-producing bacteria and may inhibit bacterial growth. Used in the prevention and dissolution of uroliths, but in dogs causes a dose-related, reversible hemolytic anemia and blood dyscrasia. Abbreviated AHA.
Wikipedia on Answers.com:
Top
Acetohydroxamic acid
 |
|
|---|---|
 |
|
| Systematic (IUPAC) name | |
| ethanehydroxamic acid | |
| Clinical data | |
| AHFS/Drugs.com | Consumer Drug Information |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 546-88-3  |
| ATC code | G04BX03 |
| PubChem | CID 1990 |
| DrugBank | DB00551 |
| ChemSpider | 1913 |
| UNII | 4RZ82L2GY5 |
| KEGG | D00220 |
| ChEBI | CHEBI:49029 |
| ChEMBL | CHEMBL734 |
| Chemical data | |
| Formula | C2H5NO2 |
| Mol. mass | 75.0666 g/mol |
| SMILES | eMolecules & PubChem |
|
|
 (what is this?) (verify) |
|
Acetohydroxamic acid (also known as AHA or Lithostat) is a drug that is a potent and irreversible inhibitor of bacterial and plant urease usually used for urinary tract infections. The molecule is similar to urea but is not hydrolyzable by the urease enzyme (Fishbein and Carbone, 1965).
References
- W. Fishbein and P. Carbone J Biol Chem. 1965 Jun;240:2407-14
See also
|
||||||||||||||||
 |
This drug article relating to the genito-urinary system is a stub. You can help Wikipedia by expanding it. |
This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)
Post a question - any question - to the WikiAnswers community:
Copyrights:
Saunders Veterinary Dictionary
Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.
Read more
