Aclarubicin
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Aclarubicin
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| Systematic (IUPAC) name | |
| Methyl (1R,2R,4S)-4-[(2R,5S,6S)-4-dimethylamino-5-[(2S,4S,5S,6S)-4-hydroxy-6-methyl | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | ? |
| Legal status | ℞ Prescription only |
| Routes | IV |
| Identifiers | |
| CAS number | 57576-44-0  |
| ATC code | L01DB04 |
| PubChem | CID 42474 |
| ChemSpider | 1931  |
| UNII | 74KXF8I502 |
| KEGG | D02756 |
| ChEMBL | CHEMBL1697719 |
| Chemical data | |
| Formula | C42H53NO15 |
| Mol. mass | 811.86 g/mol |
| SMILES | eMolecules & PubChem |
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Aclarubicin (INN) or Aclacinomycin A[1] is an anthracycline drug[2] that is used in the treatment of cancer. Soil bacteria Streptomyces galilaeus can produce aclarubicin.
References
- ^ Alcarubicin - PubChem
- ^ Jensen PB, Jensen PS, Demant EJ, et al. (October 1991). "Antagonistic effect of aclarubicin on daunorubicin-induced cytotoxicity in human small cell lung cancer cells: relationship to DNA integrity and topoisomerase II". Cancer Res. 51 (19): 5093–9. PMID 1655244. http://cancerres.aacrjournals.org/cgi/pmidlookup?view=long&pmid=1655244.
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