ACN is a three-letter acronym that may refer to:

• Accenture (NYSE: ACN)
• Acetonitrile
• Achnasheen railway station (National Rail code: ACN), a United Kingdom railway station
• Acn, abbreviation for the orchid genus Acineta
• ACN Inc., multi-level marketing company selling telecommunications services
• Acrylonitrile
• Action Congress of Nigeria, political party of Nigeria
• Africa Cup of Nations, biennual football tournament held in Africa and organised by the CAF
• Agencia Carabobeña de Noticias, news agency based in Valencia, Venezuela
• Aid to the Church in Need, international Catholic charity based in Königstein im Taunus, Germany
• Aircraft Classification Number, ICAO standard number indicating the pavement load imposed by an aircraft
• American Collectibles Network, former name of the American television network now known as Jewelry Television
• Anglican Communion Network, missionary organisation based in Pittsburgh, USA
• Ante Christum Natum, Latin equivalent of B.C., seldom used in English
• Application Context Name (Used in Network/Communication protocols per ETSI standards)
• Architecture for Control Networks, network protocol for theatrical control
• Australian Company Number, number issued by the Australian Securities and Investments Commission to registered companies

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