adenosine 3′,5′-phosphate

symbol: Ado-3′,5′-P; the recommended name for cyclic adenosine 3′,5′-monophosphate (abbr.: cyclic AMP or cAMP); adenosine 3′,5′-cyclophosphate; adenosine 3′,5′-(cyclic)phosphate; a monophosphoric diester of adenosine. It is a universally distributed key metabolite, produced by the action of adenylate cyclase on adenosine 5′-triphosphate, ATP. The first compound to be named a second messenger, it mediates many effects in signal transduction pathways. It was first identified as a heat-stable activator of glycogen phosphorylase kinase, and is now known also to activate cyclic-AMP-dependent protein kinase and to regulate numerous other enzymic activities or physiological processes.

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