adenosine 3′-phosphate 5′-phosphosulfate
Oxford Dictionary of Biochemistry:
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adenosine 3′-phosphate 5′-phosphosulfate
or 3′-phosphoadenosine 5′-phosphosulfate
symbol: PAdoPS; abbr.: PAPS; alternative recommended names for active sulfate; 3′-phospho-5′-adenylyl sulfate; adenosine 3′-phosphate 5′-P-phosphatosulfate; 3′-phospho-5′-adenylic sulfuric monoanhydride; a naturally occurring mixed anhydride. It is synthesized from adenosine 5′-phosphosulfate by phosphorylation with ATP through the action of adenylylsulfate kinase (EC 2.7.1.25). It is an intermediate in the formation of a variety of sulfo compounds in biological systems. For example, in animals it is involved in sulfate transfer in the formation of sulfatides and in the synthesis of chondroitin sulfate and other sulfated polysaccharides, while in bacteria, by a process analogous to that involving adenosine 5′-phosphosulfate in plants, adenosine 3′-phosphate 5′-phosphosulfate interacts with reduced thioredoxin to yield adenosine 3′,5′-bis(phosphate) and sulfite; the latter can then undergo further reduction to sulfide, from which cysteine may be synthesized.
symbol: PAdoPS; abbr.: PAPS; alternative recommended names for active sulfate; 3′-phospho-5′-adenylyl sulfate; adenosine 3′-phosphate 5′-P-phosphatosulfate; 3′-phospho-5′-adenylic sulfuric monoanhydride; a naturally occurring mixed anhydride. It is synthesized from adenosine 5′-phosphosulfate by phosphorylation with ATP through the action of adenylylsulfate kinase (EC 2.7.1.25). It is an intermediate in the formation of a variety of sulfo compounds in biological systems. For example, in animals it is involved in sulfate transfer in the formation of sulfatides and in the synthesis of chondroitin sulfate and other sulfated polysaccharides, while in bacteria, by a process analogous to that involving adenosine 5′-phosphosulfate in plants, adenosine 3′-phosphate 5′-phosphosulfate interacts with reduced thioredoxin to yield adenosine 3′,5′-bis(phosphate) and sulfite; the latter can then undergo further reduction to sulfide, from which cysteine may be synthesized.
| adenosine 3′,5′-phosphate, adenosine, adenoma | |
| adenosine 5′-[α,β-methylene]diphosphate, adenosine 5′-[β,γ-imido]triphosphate, adenosine 5′-[β,γ-methylene]triphosphate |
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Oxford Dictionary of Biochemistry
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