molecules expressed on the surface of a cell that mediate the adhesion of the cell to other cells, or to the extracellular matrix. They bind to receptors, classed collectively as
integrins. Adhesion molecules are grouped into classes: these include
selectins; the immunoglobulin superfamily, containing
ICAM,
MadCAM,
NCAM,
PECAM, and
VCAM; the
cadherins; and
CD44. Adhesion molecules play a part in morphogenesis (e.g., cadherins), and in the treatment of inflammation and wounds (e.g., selectins and the immunoglobulin superfamily).