Afutuzumab
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Afutuzumab
| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Humanized (from mouse) |
| Target | CD20 |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 949142-50-1  |
| ATC code | None |
| UNII | O43472U9X8  |
| KEGG | D09321 |
| Chemical data | |
| Formula | C6512H10060N1712O2020S44 |
| Mol. mass | 146.1 kDa |
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Afutuzumab is a monoclonal antibody being developed by Hoffmann-La Roche Inc. for the treatment of lymphoma.[1] It acts as an immunomodulator.[2][3] It was renamed obinutuzumab in 2009.[4]
References
- ^ Robak, T (2009). "GA-101, a third-generation, humanized and glyco-engineered anti-CD20 mAb for the treatment of B-cell lymphoid malignancies". Current opinion in investigational drugs (London, England : 2000) 10 (6): 588–96. PMID 19513948.
- ^ Statement On A Nonproprietary Name Adopted By The Usan Council - Afutuzumab, American Medical Association.
- ^ International Nonproprietary Names for Pharmaceutical Substances (INN), World Health Organization.
- ^ International Nonproprietary Names for Pharmaceutical Substances (INN), World Health Organization.
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