agammaglobulinemia
American Heritage Dictionary:
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a·gam·ma·glob·u·lin·e·mi·a
(ā-găm'ə-glŏb'yə-lə-nē'mē-ə) 
n.
A congenital or acquired deficiency of gamma globulins in the blood.
n.
A congenital or acquired deficiency of gamma globulins in the blood.
American Heritage Stedman's Medical Dictionary:
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a·gam·ma·glob·u·lin·e·mi·a
(ā-găm'ə-glŏb'yə-lə-nē'mē-ə)
n.
n.
Congenital or acquired absence of, or extremely low levels of, gamma globulins in the blood.
Oxford Dictionary of Biochemistry:
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agammaglobulinemia
or (esp. Brit.) agammaglobulinaemia
a disease characterized by early onset of recurrent infections, profound hypogammaglobulinemia (of IgM, IgA, and IgG) and almost total absence of B lymphocytes in the peripheral circulation. An X-linked form is associated with over 400 mutations in a locus for Bruton's tyrosine protein kinase at Xq22. An autosomal recessive form is associated with at least four mutations in a locus at 14q32.3 encoding the mu heavy chain.
a disease characterized by early onset of recurrent infections, profound hypogammaglobulinemia (of IgM, IgA, and IgG) and almost total absence of B lymphocytes in the peripheral circulation. An X-linked form is associated with over 400 mutations in a locus for Bruton's tyrosine protein kinase at Xq22. An autosomal recessive form is associated with at least four mutations in a locus at 14q32.3 encoding the mu heavy chain.
| aflatoxin, affinoelectrophoresis, affinity-purified | |
| agamogeny, agar, agar-diffusion method |
Saunders Veterinary Dictionary:
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agammaglobulinemia
Severe or complete deficiency of immunoglobulins (antibodies) in the blood. Due to reliance on colostral versus placental transfer of immunoglobulins most domestic animals are agammaglobulinemic at birth, prior to suckling. An inherited defect is not commonly recorded in animals, but does occur as a primary inherited condition and as part of a combined immune deficiency, both of them in horses. The deficiency or absence of antibodies results in severe and recurrent infections. See also hypogammaglobulinemia, combined immune deficiency syndrome (disease).
- Bruton's a. — an inherited, X-linked recessive condition in humans involving a deficiency of B lymphocytes and plasma cells. A similar condition, though less well characterized, has been recognized in horses.
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American Heritage Dictionary
The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved.
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American Heritage Stedman's Medical Dictionary
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company.
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Oxford Dictionary of Biochemistry
Oxford University Press. Oxford Dictionary of Biochemistry and Molecular Biology © 1997, 2000, 2006 All rights reserved.
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