agenesis

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(ā-jĕn'ĭ-sĭs) pronunciation
n.
Absence or incomplete development of an organ or body part.



Failure of all or part of an organ to develop during embryonic growth. Many forms of agenesis are lethal, such as absence of the entire brain (anencephaly), but agenesis of one organ of a pair may cause little problem. Agenesis of a kidney, bladder, testicle, ovary, thyroid, and lung are known. Agenesis of the arms or legs is called meromelia (absence of one or both hands or feet), phocomelia (normal hands and feet but no arms or legs), and amelia (complete absence of a limb or limbs). Agenesis may be caused by absence of embryonic tissue or by chemical exposure in the uterus, and it is often associated with other congenital disorders.

For more information on agenesis, visit Britannica.com.

Absence of an organ due to nonappearance of its primordium in the embryo.

(ājen′əsis)
n

The defective development or congenital absence of parts.

In medicine, agenesis refers to the failure of an organ to develop during embryonic growth and development due to the absence of primordial tissue. Many forms of agenesis are referred to by individual names, depending on the organ affected:

Contents

Eye agenesis

Eye agenesis is a medical condition in which sufferers are born with no eyes.

Dental & oral agenesis

Ear agenesis

Ear agenesis is a medical condition in which people are born without ears.

Because the middle and inner ears are necessary for hearing, people with complete agenesis of the ears suffer from total deafness. Minor agenesis that affects only the visible parts of the outer ear, which may be called microtia, typically produces cosmetic concerns and perhaps hearing impairment if the opening to the ear canal is blocked, but not deafness.

References


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