AH-7921
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AH-7921
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| Systematic (IUPAC) name | |
| 3,4-dichloro-N-[(1-dimethylamino)cyclohexylmethyl]benzamide | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 55154-30-8  |
| ATC code | None |
| PubChem | CID 187760 |
| ChemSpider | 163208  |
| Synonyms | AH-7921 |
| Chemical data | |
| Formula | C16H22Cl2N2O |
| Mol. mass | 329.265 g/mol |
| SMILES | eMolecules & PubChem |
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AH-7921 is an opioid analgesic drug selective for the µ-opioid receptor, having around 80% the potency of morphine when administered orally[1][2]. It was discovered in the 1970s[3] by a team at Allan and Hanbury's.
References
- ^ Brittain, R. T.; Kellett, D. N.; Neat, M. L.; Stables, R. (1973). "Proceedings: Anti-nociceptive effects in N-substituted cyclohexylmethylbenzamides". British journal of pharmacology 49 (1): 158P–159P. PMC 1776456. PMID 4207044. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1776456.
- ^ Hayes, A. G.; Tyers, M. B. (1983). "Determination of receptors that mediate opiate side effects in the mouse". British journal of pharmacology 79 (3): 731–736. PMC 2044905. PMID 6317119. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2044905.
- ^ Harper, Norman; Veitch, George (1976-08-17). "US Patent 3975443". US Patent Office. Allen & Hanburys Limited. http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=3,975,443.PN.&OS=PN/3,975,443&RS=PN/3,975,443. Retrieved 2012-03-06.
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