Ah receptor

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abbr. for aryl hydrocarbon receptor; a protein, encoded by the Ah gene, that binds a number of aryl hydrocarbons and mediates their biochemical and toxic effects. It is activated when it binds a ligand, and then translocates from the cytoplasm to the nucleus, where it is believed to enhance gene transcription by binding to the xenobiotic-response element sequence. It contains a basic helix-turn-helix motif; the DNA-binding form is a heterodimer of this protein and ARNT.

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