alanine-glyoxylate aminotransferase
Oxford Dictionary of Biochemistry:
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alanine-glyoxylate aminotransferase
EC 2.6.1.44; a hepatic peroxisomal pyridoxal phosphate-dependent enzyme that catalyses the reaction:
alanine + glyoxylate = pyruvate + glycine.
Examples from six mammalian species show 78 — 89% sequence identity. Inactivating mutations in the gene for the human enzyme (392 amino acids) lead to hyperoxaluria type 1.
| alanine transaminase, alanine scanning mutagenesis, alanine | |
| alaninium, alanino, alaninol |
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Oxford Dictionary of Biochemistry
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