Share on Facebook Share on Twitter Email
Answers.com

Alglucerase

 
Drug Info: Alglucerase

Brand names: Ceredase®



Alglucerase Solution for injection

What is this medicine?

ALGLUCERASE is a drug that is used to replace an enzyme that is missing in patients with Gaucher's disease. It is used to treat the symptoms of Gaucher's disease. It is not a cure.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
• an unusual or allergic reaction to alglucerase, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years old for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

What may interact with this medicine?

Interactions are not expected.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor for regular checks on your progress. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• blue fingernails or lips
• breathing problems
• chest pain
• cough
• flushing
• low blood pressure

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
• diarrhea
• fever, chills
• headache
• nausea, vomiting
• pain at site where injected
• stomach upset

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

Last updated: 7/1/2002

Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.

Search unanswered questions...
Enter a question here...
Search: All sources Community Q&A Reference topics
Wikipedia: Alglucerase
Top
Alglucerase
Systematic (IUPAC) name
Human Beta-glucocerebrosidase
Identifiers
CAS number 37228-64-1
ATC code A16AB01
PubChem  ?
DrugBank BTD00037
Chemical data
Formula C2532H3854N672O711S16 
Mol. mass 55597.4 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 3.6–10.4 min
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Alglucerase is a modified form of human β-glucocerebrosidase where the non-reducing ends of the oligosaccharide chains have been terminated with mannose residues. Ceredase is a citrate buffered solution of Alglucerase manufactured by Genzyme Corporation from human placental tissue. It is given intravenously in the treatment of Type 1 Gaucher's disease although it has been largely replaced by Cerezyme which is produced by Recombinant DNA technology.

External links


 
 
Learn More
Alglucerase Solution for injection
Gaucher Disease: Treatment
Lipidoses: Treatment

Post a question - any question - to the WikiAnswers community:

 

Copyrights:

Drug Info. Gold Standard. Copyright © 2008 by Gold Standard. All rights reserved.  Read more
Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Alglucerase" Read more