Alkenylglycerophosphoethanolamine hydrolase
Oxford Dictionary of Biochemistry:
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alkenylglycerophosphoethanolamine hydrolase
EC 3.3.2.5; a phospholipase enzyme involved in the turnover of plasmalogens. It catalyses the hydrolysis of 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine to an aldehyde and sn-glycero-3-phosphoethanolamine.
| alkenylglycerophosphocholine hydrolase, alkenyl, alkatrienyl | |
| alkyl, alkylating agent, alkylation |
Wikipedia on Answers.com:
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Alkenylglycerophosphoethanolamine hydrolase
| alkenylglycerophosphoethanolamine hydrolase | |||||||
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| Identifiers | |||||||
| EC number | 3.3.2.5 | ||||||
| CAS number | 78413-08-8 | ||||||
| Databases | |||||||
| IntEnz | IntEnz view | ||||||
| BRENDA | BRENDA entry | ||||||
| ExPASy | NiceZyme view | ||||||
| KEGG | KEGG entry | ||||||
| MetaCyc | metabolic pathway | ||||||
| PRIAM | profile | ||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||
| Gene Ontology | AmiGO / EGO | ||||||
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In enzymology, an alkenylglycerophosphoethanolamine hydrolase (EC 3.3.2.5) is an enzyme that catalyzes the chemical reaction
- 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O
an aldehyde + sn-glycero-3-phosphoethanolamine
Thus, the two substrates of this enzyme are 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine and H2O, whereas its two products are aldehyde and sn-glycero-3-phosphoethanolamine.
This enzyme belongs to the family of hydrolases, specifically those acting on ether bonds (ether hydrolases). The systematic name of this enzyme class is 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine aldehydohydrolase. This enzyme participates in ether lipid metabolism.
References
- Gunawan J, Debuch H (1981). "Liberation of free aldehyde from 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine (lysoplasmalogen) by rat liver microsomes". Hoppe. Seylers. Z. Physiol. Chem. 362 (4): 445–52. doi:10.1515/bchm2.1981.362.1.445. PMID 7239443.
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Oxford Dictionary of Biochemistry
Oxford University Press. Oxford Dictionary of Biochemistry and Molecular Biology © 1997, 2000, 2006 All rights reserved.
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