American endocrinologist (1892–1943)
Allen, the son of a physician, was born in Canon City, Colorado, and educated at Brown University. After war service he worked at Washington University, St. Louis, before being appointed (1923) to the chair of anatomy at the University of Missouri. In 1933 he moved to a similar post at Yale and remained there until his death.
In 1923 Allen, working with Edward Doisy, began the modern study of the sex hormones. It was widely thought that the female reproductive cycle was under the control of some substance found in the corpus luteum, the body formed in the ovary after ovulation. Allen thought rather that the active ingredient was probably in the follicles surrounding the ovum. To test this he made an extract of the follicular fluid and found that on injection it induced the physiological changes normally found only in the estrous cycle. Allen had in fact discovered estrogen although it was only identified some six years later by Adolf Butenandt.
| Edgar Allen | |
|---|---|
Edgar Allen (2nd from left) |
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| Born | May 2, 1892 Canon City, Colorado |
| Died | February 3, 1943 (aged 50) New Haven, Connecticut |
| Residence | |
| Nationality | |
| Fields | Anatomy, Physiology, Endocrinology |
| Institutions | University of Missouri, Washington University, Yale University |
| Alma mater | Brown University |
Edgar Allen (May 2, 1892 – February 3, 1943) was an American anatomist and physiologist. He is known for the discovery of estrogen and his role in creating the field of endocrinology.[1]
Born on Cañon (Canyon) City, Colorado, Allen was educated at Brown University. After serving in World War I he took a position at Washington University in St. Louis until, in 1923, he was appointed to the chair of anatomy at the University of Missouri in Columbia, Missouri. Ten years later he was appointed to the chair at Yale University.
At Missouri, he began his studies of sex hormones. While it was commonly believed at the time that the female reproductive cycle was controlled by substance in the corpus luteum, Allen sought the answer in the follicles surrounding the ovum, leading to his discovery of estrogen, though it was identified six years later by Adolf Butenandt.
Allen died of a heart attack in 1943 while on duty with the United States Coast Guard.
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