Alpha-Naphthylthiourea

α-Naphthylthiourea
IUPAC name naphthalen-1-ylthiourea
Identifiers
Abbreviations	ANTU
CAS number	86-88-4 N
PubChem	736366
ChemSpider	643492 Y
KEGG	C19136 N
Jmol-3D images	Image 1 Image 2
SMILES C1=CC=C2C(=C1)C=CC=C2NC(=S)N S=C(N)Nc2cccc1ccccc12
InChI InChI=1S/C11H10N2S/c12-11(14)13-10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,(H3,12,13,14) Y Key: PIVQQUNOTICCSA-UHFFFAOYSA-N Y InChI=1/C11H10N2S/c12-11(14)13-10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,(H3,12,13,14) Key: PIVQQUNOTICCSA-UHFFFAOYAV
Properties
Molecular formula	C11H10N2S
Molar mass	202.28 g/mol
Hazards
Main hazards	Toxic
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

α-Naphthylthiourea (ANTU, Dirax) is an organosulfur compound. It is a derivative of thiourea and used as a rodenticide. It acts by inducing pulmonary edema and has relatively selective toxicity for rats.^[1]

Safety

Currently, the substance is banned for use in plant protection by the UK government.^[2]

References

1. ^ Sipahi EY, Ozel Tekin I, Comert M, Barut F, Ustun H, Sipahi TH. Oxidized low-density lipoproteins accumulate in rat lung after experimental lung edema induced by alpha- naphthylthiourea (ANTU). Pharmacological Research. 2004 Dec;50(6):585-91. PMID 15501696
2. ^ http://www.pesticides.gov.uk/approvals.asp?id=55

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