Alpha-v beta-5
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Alpha-v beta-5
αVβ5 is a type of integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis. However, recent studies indicate that it actually inhibits angiogenesis.[1]
It consists of two components, integrin alpha V and integrin beta 5.
References
- ^ Sheppard D (October 2002). "Endothelial integrins and angiogenesis: not so simple anymore". J. Clin. Invest. 110 (7): 913–4. doi:10.1172/JCI16713. PMC 151161. PMID 12370267. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=151161.
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