Amezinium metilsulfate
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Amezinium metilsulfate
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| Systematic (IUPAC) name | |
| 6-Methoxy-1-phenylpyridazin-1-ium-4-amine; methyl sulfate | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | ? |
| Legal status | ℞ Prescription only |
| Routes | Oral |
| Identifiers | |
| CAS number | 30578-37-1  |
| ATC code | C01CA25 |
| PubChem | CID 71926 |
| ChemSpider | 64937  |
| UNII | 03NR868ICX |
| KEGG | D01304 |
| Chemical data | |
| Formula | C12H15N3O5S |
| Mol. mass | 313.32 g/mol |
| SMILES | eMolecules & PubChem |
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Amezinium metilsulfate (INN, trade name Regulton) is a sympathomimetic drug used for the treatment of low blood pressure. It has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition of noradrenaline and tyramine uptake.[1][2]
References
- ^ Araújo, D; Caramona, MM; Osswald, W (1983). "On the mechanism of action of amezinium methylsulphate on the dog saphenous vein". European journal of pharmacology 90 (2-3): 203–14. doi:10.1016/0014-2999(83)90238-8. PMID 6873182.
- ^ Lenke, D; Gries, J; Kretzschmar, R (1981). "Pharmacology of amezinium, a novel antihypotensive drug. III. Studies on the mechanism of action". Arzneimittel-Forschung 31 (9a): 1558–65. PMID 7197970.
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