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Amfenac

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Amfenac
Systematic (IUPAC) name
2-Amino-3-benzoylphenylacetic acid
2-Amino-3-benzoylbenzeneacetic acid
2-(2-amino-3-benzoyl-phenyl)acetic acid
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 51579-82-9 YesY
ATC code None
PubChem CID 2136
ChemSpider 2051 YesY
UNII 28O5C1J38A YesY
KEGG D07443 YesY
ChEMBL CHEMBL25146 YesY
Chemical data
Formula C15H13NO3 
Mol. mass 255.27 g/mol
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

Amfenac (2-Amino-3-benzoylbenzeneacetic acid) is a non-steroidal anti-inflammatory drug with acetic acid moiety.

Chemistry

Amfenac synth.png

Welstead, William J.; Moran, H. Wayne; Stauffer, Harold F.; Turnbull, Lennox B.; Sancilio, Lawrence F. (1979). "Antiinflammatory agents. 1. Synthesis and antiinflammatory activity of 2-amino-3-benzoylphenylacetic acid". Journal of Medicinal Chemistry 22 (9): 1074–9. doi:10.1021/jm00195a012. PMID 490552. 

v · d · eAnti-inflammatory products (M01A)
Pyrazolidine/Butylpyrazolidines
Acetic acid derivatives
and related substances
Oxicams
Propionic acid derivatives
Fenamates
Coxibs
Other

M: MUS, DF+DRCT

anat (h/n, u, t/d, a/p, l)/phys/devp/hist

noco(m, s, c)/cong(d)/tumr, sysi/epon, injr

proc, drug (M1A/3)
v · d · eNon-steroidal anti-inflammatory drug (NSAID) products (primarily M01A and M02A, also N02BA)
Salicylates
Arylalkanoic acids
2-Arylpropionic acids
(profens)
N-Arylanthranilic acids
(fenamic acids)
Pyrazolidine derivatives
Oxicams
COX-2 inhibitors
Celecoxib • Deracoxib‡ • Etoricoxib • Firocoxib‡ • Lumiracoxib† • Parecoxib • Rofecoxib† • Valdecoxib†
Sulfonanilides
Topically used products
COX-inhibiting nitric oxide donators
Others
Items listed in bold indicate initially developed compounds of specific groups. †Withdrawn drugs. ‡Veterinary use medications.
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