Amine oxidase

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(copper-containing)

EC 1.4.3.6; other names: diamine oxidase; diamino oxhydrase; histaminase; an enzyme that catalyses the oxidation by dioxygen of an amino group to an aldehyde, with release of ammonium and hydrogen peroxide. 6-Hydroxydopa and copper are cofactors. Example, human amiloride-sensitive amine oxidase (copper-containing) precursor (amiloride-binding protein;abbr.: ABP), an 85.27 kDa enzyme that binds amiloride.

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Ribbon representation of human diamine oxidase.[1]
amiloride binding protein 1 (amine oxidase (copper-containing))
Identifiers
Symbol ABP1
Entrez 26
HUGO 80
OMIM 104610
RefSeq NM_001091
UniProt P19801
Other data
EC number 1.4.3.6
Locus Chr. 7 q34-qter

Amine oxidase is an enzyme involved in the metabolism of histamine.

External links

References

  1. ^ PDB 3HI7; McGrath AP, Hilmer KM, Collyer CA, Shepard EM, Elmore BO, Brown DE, Dooley DM, Guss JM (2009). "Structure and inhibition of human diamine oxidase". Biochemistry 36: 9810–9822. doi:10.1021/bi9014192. PMID 19764817. ; rendered with PyMOL



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