Amino acid neurotransmitter
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Amino acid neurotransmitter
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Activity at an axon terminal: Neuron A is transmitting a signal at the axon terminal to neuron B (receiving). Features: 1. Mitochondrion. 2. synaptic vesicle with neurotransmitters. 3. Autoreceptor. 4. Synapse with neurotransmitter released (serotonin). 5. Postsynaptic receptors activated by neurotransmitter (induction of a postsynaptic potential). 6. Calcium channel. 7. Exocytosis of a vesicle. 8. Recaptured neurotransmitter. |
An amino acid neurotransmitter is a chemical substance which is able to transmit a nerve message across a synapse. Neurotransmitters (chemicals) are packaged into vesicles that cluster beneath the axon terminal membrane on the presynaptic side of a synapse in a process called endocytosis.[1] Amino acid neurotransmitter release (exocytosis) is dependent upon calcium Ca2+ and is a presynaptic response. There are inhibitory amino acids (IAA) or excitatory amino acids (EAA). Some EAA are L-Glutamate, L-Aspartate, L-Cysteine, and L-Homocysteine.[2] These neurotransmitter systems will activate post-synaptic cells.[3] Some IAA include GABA, Glycine, β-Alanine, and Taurine.[2] The IAA depress the activity of post-synaptic cells.[3]
- See also Amino acid non protein functions
References
- ^ "Axon Terminal : on Medical Dictionary Online". http://www.online-medical-dictionary.org/Axon+Terminal.asp?q=Axon+Terminal. Retrieved 2008-12-25.
- ^ a b Foye, Thomas L.,lastn= Lemke (2007). Foye's Principles of Medicinal Chemistry. David A. Williams. Lippincott Williams & Wilkins. p. 446. ISBN 0-7817-6879-9, 9780781768795.
- ^ a b D'haenen, Johan A. ,lastn=den Boer (2002) (digitised online by Google books). Biological Psychiatry. Paul Willner. John Wiley and Sons. p. 415. ISBN 0-471-49198-5, 9780471491989. http://books.google.com/?id=ZMSNFtyjtEAC. Retrieved 2008-12-26.
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