Medical Encyclopedia:
Aminoglycosides: Abnormal results
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In some cases, bacteria are resistant to antibiotics that would normally kill them. This resistance becomes apparent after repeated exposure to the antibiotic and arises from a mutation that alters the bacteria's susceptibility to the drug. Various degrees of resistance have been observed in bacteria that normally would be destroyed by aminoglycosides. In general, though, aminoglycoside effectiveness has held up well over time.
— Julia Barrett
