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Aminoquinoline

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Aminoquinoline

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Quinoline
Chloroquine (4-Aminoquinoline)
Pamaquine (8-Aminoquinoline)

Aminoquinoline are derivatives of quinoline, most notable for their roles as antimalarial drugs.

Depending upon the location of the amino group, they can be divided into:

v · d · eAntiparasitics – antiprotozoal agents – Chromalveolate antiparasitics (P01)
Alveo-
late
Individual
agents
Aminoquinolines
Other
DHFR inhibitors
(antifols)
Sulfadoxine • sulfamethoxypyrazine
Coformulation
Other
Atovaquone (as Malarone)
Tetracycline • Doxycycline#
Clindamycin
Combi-
nations
Fixed-dose (coformulated) ACTs
artemether-lumefantrine#
artesunate-amodiaquine (ASAQ)
artesunate-mefloquine (ASMQ)
dihydroartemisinin-piperaquine
artesunate-pyronaridine
Other combinations
(not co-formulated)
artesunate/SP • artesunate/mefloquine •
quinine/tetracycline • quinine/doxycycline • quinine/clindamycin
Hetero-
kont
#WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III
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4-Aminoquinoline