Analgesics, Opioid: Side effects
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More about Analgesics, Opioid:
Definition Purpose Recommended dosage Precautions Side effects Interactions |
Some people experience drowsiness, dizziness, light-headedness, or a false sense of well-being after taking opioid analgesics. Anyone who takes these drugs should not drive, use machines, or do anything else that might be dangerous until they know how the drug affects them. Nausea and vomiting are common side effects, especially when first beginning to take the medicine. If these symptoms do not go away after the first few doses, check with the physician or dentist who prescribed the medicine.
Dry mouth is another common side effect. Dry mouth can be relieved by sucking on sugarless hard candy or ice chips or by chewing sugarless gum. Saliva substitutes, which come in liquid or tablet forms, also may help. Patients who must use opioid analgesics over long periods and who have dry mouth should see their dentists, as the problem can lead to tooth decay and other dental problems.
The following side effects are less common. They usually do not need medical attention and will go away after the first few doses. If they continue or interfere with normal activity, check with the physician who prescribed the medicine.
- headache
- loss of appetite
- restlessness or nervousness
- nightmares, unusual dreams, or problems sleeping
- weakness or tiredness
- mental sluggishness
- stomach pain or cramps
- blurred or double vision or other vision problems
- problems urinating, such as pain, difficulty urinating, frequent urge to urinate, or decreased amount of urine
- constipation.
Other side effects may be more serious and may require quick medical attention. These symptoms could be signs of an overdose. Get emergency medical care immediately.
- cold, clammy skin
- bluish discoloration of the skin
- extremely small pupils
- serious difficulty breathing or extremely slow breathing
- extreme sleepiness or unresponsiveness
- severe weakness
- confusion
- severe dizziness
- severe drowsiness
- slow heartbeat
- low blood pressure
- severe nervousness or restlessness
In addition, these less common side effects do not require emergency medical care, but should have medical attention as soon as possible:
- hallucinations or a sense of unreality
- depression or other mood changes
- ringing or buzzing in the ears
- pounding or unusually fast heartbeat
- itching, hives, or rash
- facial swelling
- trembling or twitching
- dark urine, pale stools, or yellow eyes or skin (after taking propoxyphene)
- increased sweating, red or flushed face (more common after taking hydrocodone and meperidine)
— Nancy Ross-Flanigan






