anaplasia

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(ăn'ə-plā'zhə) pronunciation
n.
Reversion of cells to an immature or a less differentiated form, as occurs in most malignant tumors.


(ăn'ə-plā'zhə)
n.

Reversion of cells to an immature or a less differentiated form, as occurs in most malignant tumors.


the reversion by a cell or tissue to a more primitive, embryonic, or undifferentiated form with loss of its characteristics and increased capacity for multiplication.

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Loss of differentiation of cells, an irreversible alteration in adult cells toward more primitive (embryonic) cell types; a characteristic of tumor cells.

(an′əplā′zhə)
n

A regressive change in cells toward a more primitive or embryonic cell type. Anaplasia is a prominent criterion of malignancy in tumors.

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