anaplerosis

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  1. the filling up of a deficiency; the repair or replacement of losses, especially of tissue.
  2. (in biochemistry) the process in which an intermediate in the tricarboxylic-acid cycle is replenished through a distinct anaplerotic metabolic pathway. This prevents the cycle from ceasing to function because of withdrawal of the intermediate for some other metabolic purpose. [From Greek ana, again, back, up + plerosin, to fill.]
anaplerotic adj.

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