Andrew Lees

Andrew John Lees (born in 1947 in Merseyside, England) is an English neurologist. He is Professor of Neurology at the National Hospital for Neurology and Neurosurgery, Queen Square, London and Director of the Reta Lila Weston Institute of Neurological Studies at University College, London. In 2011 he was named as the world's most highly cited Parkinson's disease researcher.

Professor Andrew John Lees

Career

Lees studied at the Royal London Hospital in Whitechapel where he was awarded the Jonathan Hutchinson Prize for Clinical Medicine, and trained as a neurologist at the Pitié-Salpêtrière Hospital, Paris, University College Hospital and at the National Hospital for Neurology and Neurosurgery.^[1] He was appointed Consultant Neurologist to the National Hospital for Neurology and Neurosurgery, Queen Square and University College Hospital at the age of 33 years.

Lees has been Director of the Reta Lila Weston Institute of Neurological Studies at University College London since 1998:^[2] under his direction the Institute has focused on clinical, pathological and genetic research into neurodegenerative diseases. He is also Director of the Queen Square Brain Bank for Neurological Disorders and the Sara Koe PSP Research Centre.

Lees is the past President of the Movement Disorders Society, and Former Co-Editor-in-Chief of the journal Movement Disorders.

Awards and achievements

Lees received the AAN Movement Disorders Life Time Achievement Award 2006,^[3] San Diego and delivered the Gowers Memorial Lecture "In search of the lost mystery of neurology" at the National Hospital in 2006, the 1st Lord Brain Memorial Lecture at the Royal London Hospital, June 2010 and the David Marsden Memorial Lecture at the EFNS Budapest September 2011. He is a Fellow of the Academy of Medical Sciences^[4] and a NIHR Senior investigator.^[5] He was awarded Honorary Membership by the Movement Disorder Society in 2010. He delivered the 8th Athasit Vejajiva Lecture, Mahidol University, Bangkok, Thailand 2007.

He is Chairman of the Medical Advisory Panel of the PSP Association (Europe ^[6] and an advisor to the Medical Research Council (UK). He also sat on the UK Government NCCC Guideline Development Group for Parkinson’s Disease (2006). He is a visiting Professor to both the University of Liverpool and Hospital Sao Rafaele, Salvador, Brazil. He is an elected overseas member of fourteen national neurological societies and a Honorary overseas member of the Academia Nacional de Medicina, Brazil.

Selected publications

Lees is recognised as a Highly Cited Neuroscientist on the ISI "Highly Cited Researchers" database with an H-index of 94 and is the world's most highly cited Parkinson's disease researcher with over 23,000 citations since 1985 and co-author of 8 citation classics.^[7][8]

Journal articles

• Compta, Y.; Parkkinen, L.; O'Sullivan, S. S.; Vandrovcova, J.; Holton, J. L.; Collins, C.; Lashley, T.; Kallis, C. et al (2011). "Lewy- and Alzheimer-type pathologies in Parkinson's disease dementia: Which is more important?". Brain 134 (5): 1493–505. doi:10.1093/brain/awr031. PMID 21596773. 
• Höglinger, Günter U; Melhem, Nadine M; Dickson, Dennis W; Sleiman, Patrick M A; Wang, Li-San; Klei, Lambertus; Rademakers, Rosa; De Silva, Rohan et al (2011). "Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy". Nature Genetics 43 (7): 699–705. doi:10.1038/ng.859. PMC 3125476. PMID 21685912. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3125476. 
• Ling, H.; O'Sullivan, S. S.; Holton, J. L.; Revesz, T.; Massey, L. A.; Williams, D. R.; Paviour, D. C.; Lees, A. J. (2010). "Does corticobasal degeneration exist? A clinicopathological re-evaluation". Brain 133 (7): 2045–57. doi:10.1093/brain/awq123. PMID 20584946. 
• Jahanshahi, M.; Jones, C. R. G.; Zijlmans, J.; Katzenschlager, R.; Lee, L.; Quinn, N.; Frith, C. D.; Lees, A. J. (2010). "Dopaminergic modulation of striato-frontal connectivity during motor timing in Parkinson's disease". Brain 133 (3): 727–45. doi:10.1093/brain/awq012. PMID 20305278. 
• Kempster, P. A.; O'Sullivan, S. S.; Holton, J. L.; Revesz, T.; Lees, A. J. (2010). "Relationships between age and late progression of Parkinson's disease: A clinico-pathological study". Brain 133 (6): 1755–62. doi:10.1093/brain/awq059. PMID 20371510. 
• Djamshidian, Atbin; Jha, Ashwani; O'Sullivan, Sean S.; Silveira-Moriyama, Laura; Jacobson, Clare; Brown, Peter; Lees, Andrew; Averbeck, Bruno B. (2010). "Risk and learning in impulsive and nonimpulsive patients with Parkinson's disease". Movement Disorders 25 (13): 2203–10. doi:10.1002/mds.23247. PMC 3093055. PMID 20721918. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3093055. 

Books

• Lees, Andrew; Stern, GM (1982). Parkinson's Disease. The facts. 
• Lees, Andrew (1985). Tics and Related Disorders. 
• Lees, Andrew (1993). Ray of Hope. London: Michael Joseph.  - a biography of Ray Kennedy, the former England football player who developed Parkinson's disease at the age of 35.
• Lees, Andrew (2011). The Hurricane Port. A social History of Liverpool. Edinburgh: Mainstream. 
• Scott, Ann; Eadie, Mervyn; Lees, Andrew (2012). William Richard Gowers 1845-1915: Exploring the Victorian Brain. Oxford University Press. 

References

External links

• Andrew J Lees Profile at University College of London
• RL Weston Institute