anserine

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(ăn'sə-rīn', -rĭn) pronunciation
adj.
  1. Of or belonging to the subfamily Anserinae, which comprises the geese.
  2. Of or resembling a goose; gooselike.

[Latin ānserīnus, pertaining to geese, from ānser, goose.]


A dipeptide found in muscle, of unknown function. It consists of β-alanine and methylhistidine.

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characteristic of a goose; silly

N-β-alanyl-Nπ-methyl-l-histidine; an isopeptide occurring in skeletal muscle and brain of some animals and humans (up to 20 mmol kg−1). Compare carnosine.





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Anserine
Identifiers
CAS number 584-85-0 YesY
PubChem 112072
ChemSpider 100482 YesY
KEGG C01262 YesY
ChEBI CHEBI:18323 YesY
ChEMBL CHEMBL448301 YesY
Jmol-3D images Image 1
Properties
Molecular formula C10H16N4O3
Molar mass 240.25904
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Anserine (beta-alanyl-N-methylhistidine) is a dipeptide found in the skeletal muscle and brain of mammals,[1] and birds.

It is an antioxidant (about 5 times that of carnosine) and helps reduce fatigue.[citation needed]

The pKa of the imidazole ring of histidine, when contained in anserine, is 7.04, making it an effective buffer at physiologic pH.[2]

See also

References

  1. ^ Quantitative studies of carnosine and anserine in mammalian muscle. 1938 (pdf)
  2. ^ Biochemistry, Garrett & Grisham

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