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Antabuse

  (ăn'tə-byūs') pronunciation

A trademark used for the drug disulfiram.


 
 

Trade name for the drug disulfiram, used in the treatment of alcoholism. It inhibits the further metabolism of acetaldehyde arising from the metabolism of alcohol, and so causes headache, nausea, vomiting, and palpitations if alcohol is consumed.

 
(ăn'təbyūs) , trade name for the drug tetraethylthiuram disulfide, used in the treatment of alcoholism. Also called sulfiram, Antabuse is nontoxic, but it alters the metabolism of alcohol in the body, making it impossible for one who is taking the drug to drink without experiencing severe discomfort. When alcohol is present the drug increases the concentration of acetaldehyde in the body, causing symptoms resembling those of a bad hangover: the individual feels hot, the face becomes flushed, the neck and head throb, and nausea, vomiting, and headache may follow. Small quantities of alcohol, such as from food sauces and cough medicines, and even inhaled traces from shaving lotions and varnishes, may induce the same symptoms. The drug Temposil, or citrated calcium carbamide, has the same function as Antabuse, but is weaker and safer. The therapeutic use of Antabuse was discovered in the 1930s when workers exposed to tetraethylthiuram disulfide, a chemical used in the rubber industry, became ill after drinking alcoholic beverages.


 
WordNet: Antabuse
Note: click on a word meaning below to see its connections and related words.

The noun has one meaning:

Meaning #1: a drug (trade name Antabuse) used in the treatment of alcoholism; causes nausea and vomiting if alcohol is ingested
  Synonym: disulfiram


 
 

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Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2007. Published by Houghton Mifflin Company. All rights reserved.  Read more
Food and Nutrition. A Dictionary of Food and Nutrition. Copyright © 1995, 2003, 2005 by A. E. Bender and D. A. Bender. All rights reserved.  Read more
Columbia Encyclopedia. The Columbia Electronic Encyclopedia, Sixth Edition Copyright © 2003, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/  Read more
WordNet. WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved.  Read more

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