anti-human thymocyte immunoglobulin

An immunoglobulin, derived from the rabbit, that acts as an antibody against lymphocytes (a type of white blood cell) produced in the thymus. It is used as an immunosuppressant to prevent rejection of kidney and heart transplants and is available as a form for injection on prescription only.

Side effects:
allergic reactions may occur, which can be minimized by giving an antihistamine and a corticosteroid before treatment. Other side effects include low white blood cell counts, fever, infection, muscle pain, breathlessness, and low blood pressure.

Precautions:
this medicine should not be given to patients with infections or to breastfeeding women and should be used with caution in pregnant women. Blood counts should be monitored during treatment.

Proprietary preparation:
Thymoglobuline.

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