Mode of action Representative antibiotics Inhibition of bacterial cell wall synthesis Penicillins Alteration of membrane permeability Cephalosporins Inhibition of microbial DNA translation and transcription Bacitracins Inhibition of essential metabolite synthesis Amphotericin B
Polymyxin B
Nystatin
Erythromycin
Tetracyclines
Streptomycin
Lincomycin
Kanamycin
Chloramphenicol
Paraminosalicylic acid
Sulfonamides
the target antigen and proliferate against it, producing mediators such as histamines. n 2. cytotoxic (Type II), antigens and antibodies that come together on the surface of a cell, causing lysis of the cell or other cell membrane damage. n 3. immune complex (Type III), a complex of antigens and antibodies that is attracted to tissue.