Antidiuretic

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  1. describing any drug or other agent that decreases the excretion of urine.
  2. an antidiuretic substance.

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1. pertaining to or causing suppression of urine production.
2. an agent that causes suppression of urine production.

  • a. hormone — vasopressin; a polypeptide hormine from the posterior lobe of the pituitary that suppresses the production of urine; it has a specific effect on the epithelial cells of the renal tubules, stimulating the reabsorption of water independently of solids, and resulting in concentration of urine. Stored and released by the posterior lobe of the pituitary gland, it also has vasopressor activity. Called also ADH.
  • a. hormone response test — measures urine specific gravity or osmolality before and after the administration of vasopressin to determine whether a polyuric condition is caused by a deficiency or reduced responsiveness to antidiuretic hormone. Called also Pitressin tannate test, Pitressin concentration test.
  • syndrome of inappropriate secretion of a. hormone (SIADH) — one in which there is abnormal production of ADH leading to hyponatremia (see also syndrome of inappropriate secretion of antidiuretic hormone).
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An antidiuretic is an agent or drug that, administered to an organism, helps control body water balance by reducing urination,[1] opposing diuresis.[2]

Contents

Uses

Antidiuretics are the drugs that reduce urine volume, particularly in diabetes insipidus (DI) which is their primary indication.

Examples

These are classified as:

  1. Antidiuretic hormones: ADH/Vasopressin, Desmopressin, Lypressin, Terlipressin
  2. Miscellaneous: Chlorpropamide, Carbamazepine

See also

References



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