Agenus

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(NASDAQ:AGEN)
Contact Information
Agenus Inc.
3 Forbes Rd.
Lexington, MA 02421
MA Tel. 781-674-4400
Fax 781-674-4200

Type: Public
On the web: http://www.agenusbio.com
Employees: 54
Employee growth: (3.6%)

Cancer and other diseases had better beware -- Agenus (formerly Antigenics) is packing heat. The firm develops heat shock proteins, which are related to the immune system's response to disease. Its patient-specific vaccines work on the theory that each person's cancer has a unique signature that can be derived from the tumor after it has been removed. The company refers to these vaccines as its Prophage Series, the lead drug candidate in the series, Oncophage, is the first personalized cancer vaccine to receive FDA fast track status, and is being developed to treat kidney and skin cancers. Agenus is also developing viral vaccines and QS-21 Stimulon, an improved vaccine adjuvant to make vaccines more effective.

Key numbers for fiscal year ending December, 2011:
Sales: $2.8M
One year growth: (18.0%)
Net income: ($23.3)M

Officers:
Chairman and CEO: Garo H. Armen
VP and CFO: Shalini Sharp
VP Clinical, Regulatory, and Quality: Kenneth A. Wentworth

Competitors:
Accentia
Dendreon
Optimer

Agenus (foremerly Antigenics Inc.) is a biotechnology company founded in 1994 by Garo H. Armen and Pramod K. Srivastava. The company focuses on cancer vaccines, immunotherapeutics, adjuvants and infectious disease treatments. Antigenics became a public company in February 2000 on the NASDAQ exchange with the ticker symbol AGEN. In 2000 Agenus acquired Aquila Biopharmaceuticals and in 2001 also acquired Aronex Pharmaceuticals. Agenus has over 80 U.S. patents, many of which relate to its proprietary heat shock protein technology upon which its experimental cancer vaccine Oncophage is built.

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CEO Garo Armen

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