antihemophilic factor

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American Heritage Dictionary:

an·ti·he·mo·phil·ic factor

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(ăn'tē-hē'mə-fĭl'ĭk, ăn'tī-) pronunciation
n. (Abbr. AHF)
A protein substance in blood plasma that participates in and is essential for the blood-clotting process. Most cases of hemophilia are caused by a deficiency of this factor. Also called antihemophilic globulin, factor VIII.



(antihaemophilic factor)

One of the factors involved in the complex process of blood clotting. Freeze-dried Factor VIII fraction, prepared from human plasma, or recombinant human antihaemophilic factor VIII (octocog alfa or moroctocog alfa), prepared by genetic engineering techniques, is used for the prevention and treatment of bleeding in people with classical haemophilia (haemophilia A; see haemostatic drugs). All preparations are available in a form for injection on prescription only.

Side effects:
include gastrointestinal upsets, alterations in taste, flushing, palpitation, breathlessness, cough, headache, dizziness, and allergic reactions, such as chills and fever.

Proprietary preparations:
Alphanate; Fanhdi; Helixate NexGen; Kogenate (octocog alfa); Octanate; ReFacto AF (moroctocog alfa); 8Y; Haemate P (combined with von Willebrand factor); Optivate (combined with von Willebrand factor).

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or antihemophilic factor A or antihemophilic globulin

an alternative name for factor VIII; see blood clotting factors.

Previous:antiglobulin test, antiglobulin consumption test, antigibberellin
Next:antihemophilic factor B, antihemophilic factor C, antihemophilic globulin

Antihemophilic factor (clotting factor VIII).


n

The abbreviation for antihemophilic factor. See also factor VIII.

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