antilymphocyte serum

Share on Facebook Share on Twitter Email
(¦an·tē′lim·fə′sīt ′sir·əm)

(immunology) An immunosuppressive agent effective in prolonging the lives of homografts in experimental animals by reducing the circulating lymphocytes.


Top
(ăn'tē-lĭm'fə-sīt', ăn'tī-)
n.

(Abbr. ALS) The globulin fraction of serum from a horse or another animal, usually used in conjunction with other immunosuppressive agents to suppress rejection of grafts or organ transplants.

Saunders Veterinary Dictionary:

antilymphocyte serum

Top

Antiserum containing antibodies specific for lymphocyte surface antigens that may be used to suppress delayed type hypersensitivity, particularly graft rejection, responses without affecting humoral immune response; abbreviated ALS. Used in organ transplantation, usually in combination with immunosuppressive drugs. Prepared by hyperimmunizing an animal, e.g. horse, with foreign, e.g. human, lymphocytes. See also antilymphocyte globulin.

Post a question - any question - to the WikiAnswers community:

Copyrights: