apoptosis protease-activating factor 1
Oxford Dictionary of Biochemistry:
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apoptosis protease-activating factor 1
abbr.: Apaf-1; a mammalian cytosolic monomeric protein (≈130 kDa) involved in triggering apoptosis. It oligomerizes on binding cytochrome c (released from mitochondria) and binds procaspase 9, which becomes autocatalytically active and promotes apoptosis.
| apoptosis inducing factor, apoptosis antigen, apoptosis | |
| apoptosome, aporepressor, apparent |
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Oxford Dictionary of Biochemistry
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