Apo
(a) or lipoprotein(a)
a plasma glycoprotein serine endopeptidase (EC 3.4.21.-). It is related to plasminogen, having 37 repeats of plasminogen kringle domains and capable of cleaving fibrinogen. Its gene is closely linked to that of plasminogen at 6q21, from which it originated by gene duplication. It is mostly covalently linked (by disulfide bond) to apolipoprotein B-100, when it forms lipoprotein (a). Its plasma concentration is related to the incidence of atherosclerosis.
a plasma glycoprotein serine endopeptidase (EC 3.4.21.-). It is related to plasminogen, having 37 repeats of plasminogen kringle domains and capable of cleaving fibrinogen. Its gene is closely linked to that of plasminogen at 6q21, from which it originated by gene duplication. It is mostly covalently linked (by disulfide bond) to apolipoprotein B-100, when it forms lipoprotein (a). Its plasma concentration is related to the incidence of atherosclerosis.
| Apm, Api, Ape | |
| Apo-1, Apollon, Ar |
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Oxford Dictionary of Biochemistry
Oxford University Press. Oxford Dictionary of Biochemistry and Molecular Biology © 1997, 2000, 2006 All rights reserved.
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