Arneth count
American Heritage Stedman's Medical Dictionary:
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Ar·neth count
(är'nĕt')
n.
n.
The analysis by percentage of the distribution of neutrophils based on the number of lobes in the nuclei, ranging from 1 to 5 lobes. Also called Arneth index.
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Arneth count
The Arneth count or Arneth index describes the nucleus of a type of white blood cell called a neutrophil in an attempt to detect disease.
Neutrophils typically have two or three lobes. In general, older neutrophils have more lobes than younger neutrophils. The Arneth count determines the percentage of neutrophils with one, two, three, four, and five or more lobes.
- Individuals who have a larger percentage of neutrophils with fewer lobes have a left shift which can be indicative of disease processes such as infection, malignant tumors, hemolytic crises, myocardial infarction, acidosis, etc.
- Individuals with a larger percentage of neutrophils with more lobes have a right shift and most commonly have diseases such as vitamin B12 or folate deficiency, chronic uremia, liver disease, etc.
The Arneth count is not commonly used in modern medicine, but is a frequent MCQ in PG entrance exams.
It is named for Josef Arneth.[1][2][3]
References
- ^ Synd/252 at Who Named It?
- ^ J. Arneth: Die neutrophilen weissen Blutkärperchen bei Infektions-Krankheiten. Habilitation paper, Jena 1903
- ^ "THE ARNETH COUNT". http://www.pubmedcentral.nih.gov/pagerender.fcgi?artid=382513&pageindex=1.
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American Heritage Stedman's Medical Dictionary
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