Asclepiades may refer to:
- Asclepiades of Phlius, (4th–3rd century BC) philosopher in the Eretrian school of Philosophy
- Asclepiades of Samos, (3rd century BC) lyric poet
- Asclepiades of Bithynia, (c. 125–40 BC) philosopher and physician
- Asclepiades Pharmacion, (1st-2nd century) Greek physician
- Asclepiades of Antioch, (d.217) Patriarch of Antioch, Christian saint and martyr
- Asclepiades, (c. 250) Christian saint and martyr (see Pionius)
- Asclepiades the Cynic, (4th century) Cynic philosopher
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