Astressin-B
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Astressin-B
Astressin-B is a nonselective corticotropin releasing hormone antagonist that reduces the synthesis of ACTH and cortisol.[1]
Reducing ACTH synthesis, it improves the sexual drive of rats under stressing conditions.[2]
In 2011, research showed that treatment with astressin-B caused the sudden growth of hair in mice bred for a propensity for stress.[3][4]
References
- ^ Vulliémoz NR, Xiao E, Xia-Zhang L, Rivier J, Ferin M (March 2008). "Astressin B, a nonselective corticotropin-releasing hormone receptor antagonist, prevents the inhibitory effect of ghrelin on luteinizing hormone pulse frequency in the ovariectomized rhesus monkey". Endocrinology 149 (3): 869–74. doi:10.1210/en.2007-1350. PMC 2275354. PMID 18063681. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2275354.
- ^ . PMID 20946165.
- ^ Rebecca Boyle (2011-02-16). "Researching Stress, Scientists May Have Accidentally Found Baldness Cure". popsci.com. http://www.popsci.com/science/article/2011-02/stress-research-may-have-accidentally-set-scientists-path-toward-baldness-cure.
- ^ Wang, L.; Million, M.; Rivier, J.; Rivier, C.; Craft, N.; Stenzel-Poore, M. P.; Taché, Y. (2011). Polymenis, Michael. ed. "CRF Receptor Antagonist Astressin-B Reverses and Prevents Alopecia in CRF Over-Expressing Mice". PLoS ONE 6: e16377. doi:10.1371/journal.pone.0016377.
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