ATP2A2
Wikipedia on Answers.com:
Top
ATP2A2
| ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | |
|---|---|
| Identifiers | |
| Symbol | ATP2A2 |
| Alt. symbols | ATP2B, DAR |
| Entrez | 488 |
| HUGO | 812 |
| OMIM | 108740 |
| RefSeq | NM_001681 |
| UniProt | P16615 |
| Other data | |
| EC number | 3.6.3.8 |
| Locus | Chr. 12 q23-q24 |
ATP2A2 is an ATPase associated with Darier's disease and Acrokeratosis verruciformis.
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.
External links
 |
This biochemistry article is a stub. You can help Wikipedia by expanding it. |
|
|||||||||||||||||||||||||||||||||||||||||||||||
This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)
Post a question - any question - to the WikiAnswers community:
Copyrights:
Wikipedia on Answers.com
This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article ATP2A2.
Read more